GrippeCanadaV3, Main, Exploration, bibRecord, 000297

Dramatically changing rates and reasons for hospitalization in multiple sclerosis.

Identifieur interne : 000297 ( Main/Exploration ); précédent : 000296; suivant : 000298

Dramatically changing rates and reasons for hospitalization in multiple sclerosis.

Auteurs : Ruth Ann Marrie [Canada] ; Lawrence Elliott [Canada] ; James Marriott [Canada] ; Michael Cossoy [Canada] ; James Blanchard [Canada] ; Aruni Tennakoon [Canada] ; Nancy Yu [Canada]

Source :

Neurology [ 1526-632X ] ; 2014.

RBID : pubmed:25085638

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Comorbidité, Durée du séjour (), Durée du séjour (tendances), Facteurs de l'âge, Facteurs sexuels, Facteurs socioéconomiques, Femelle, Hospitalisation (), Hospitalisation (tendances), Humains, Manitoba (épidémiologie), Mâle, Sclérose en plaques (), Sclérose en plaques (épidémiologie), Études de cohortes.
MESH :
- tendances : Durée du séjour, Hospitalisation.
- épidémiologie : Manitoba, Sclérose en plaques.
- Adulte, Adulte d'âge moyen, Comorbidité, Durée du séjour, Facteurs de l'âge, Facteurs sexuels, Facteurs socioéconomiques, Femelle, Hospitalisation, Humains, Mâle, Sclérose en plaques, Études de cohortes.

English descriptors

KwdEn :
- Adult, Age Factors, Cohort Studies, Comorbidity, Female, Hospitalization (statistics & numerical data), Hospitalization (trends), Humans, Length of Stay (statistics & numerical data), Length of Stay (trends), Male, Manitoba (epidemiology), Middle Aged, Multiple Sclerosis (epidemiology), Multiple Sclerosis (therapy), Sex Factors, Socioeconomic Factors.
MESH :
- geographic , epidemiology : Manitoba.
- epidemiology : Multiple Sclerosis.
- statistics & numerical data : Hospitalization, Length of Stay.
- therapy : Multiple Sclerosis.
- trends : Hospitalization, Length of Stay.
- Adult, Age Factors, Cohort Studies, Comorbidity, Female, Humans, Male, Middle Aged, Sex Factors, Socioeconomic Factors.

Abstract

OBJECTIVE

We aimed to describe hospitalizations in the multiple sclerosis (MS) population, and to evaluate temporal trends in hospitalizations in the MS population compared to the general population.

METHODS

Using population-based administrative data, we identified 5,797 persons with MS and a matched general population cohort of 28,769 persons. Using general linear models, we evaluated temporal trends in hospitalization rates and length of stay in the 2 populations over the period 1984-2011.

RESULTS

In 1984 the hospitalization rate was 35 per 100 person-years in the MS population and 10.5 in the matched population (relative risk [RR] 3.33; 95% confidence interval: 1.67-6.64). Over the study period hospitalizations declined 75% in the MS population but only 41% in the matched population. The proportion of hospitalizations due to MS declined substantially from 43.4% in 1984 to 7.8% in 2011. The 3 most common non-MS-related reasons for admission in the MS population were diseases of the digestive, genitourinary, and circulatory systems. Admissions for bacterial pneumonia, influenza, urinary tract infections, and pressure ulcers occurred more often in the MS population than in the general population, while admissions for circulatory system disease and neoplasms occurred less often. Older age, male sex, and lower socioeconomic status were associated with increased hospitalization rates for non-MS-related reasons.

CONCLUSIONS

Although hospitalization rates have declined dramatically in the MS population over the last quarter century, they remain higher than in the general population. Admissions for MS-related reasons now constitute only a small proportion of the reasons for hospitalization.

DOI: 10.1212/WNL.0000000000000753
PubMed: 25085638

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000259
to stream Main, to step Curation: 000259

Le document en format XML

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<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
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<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
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<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
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<author><name sortKey="Marrie, Ruth Ann" sort="Marrie, Ruth Ann" uniqKey="Marrie R" first="Ruth Ann" last="Marrie">Ruth Ann Marrie</name>
<affiliation wicri:level="4"><nlm:affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada. rmarrie@hsc.mb.ca.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
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<author><name sortKey="Elliott, Lawrence" sort="Elliott, Lawrence" uniqKey="Elliott L" first="Lawrence" last="Elliott">Lawrence Elliott</name>
<affiliation wicri:level="4"><nlm:affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
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<author><name sortKey="Marriott, James" sort="Marriott, James" uniqKey="Marriott J" first="James" last="Marriott">James Marriott</name>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
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<author><name sortKey="Cossoy, Michael" sort="Cossoy, Michael" uniqKey="Cossoy M" first="Michael" last="Cossoy">Michael Cossoy</name>
<affiliation wicri:level="4"><nlm:affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
<region type="state">Manitoba</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Blanchard, James" sort="Blanchard, James" uniqKey="Blanchard J" first="James" last="Blanchard">James Blanchard</name>
<affiliation wicri:level="4"><nlm:affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
<region type="state">Manitoba</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tennakoon, Aruni" sort="Tennakoon, Aruni" uniqKey="Tennakoon A" first="Aruni" last="Tennakoon">Aruni Tennakoon</name>
<affiliation wicri:level="4"><nlm:affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
<region type="state">Manitoba</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yu, Nancy" sort="Yu, Nancy" uniqKey="Yu N" first="Nancy" last="Yu">Nancy Yu</name>
<affiliation wicri:level="4"><nlm:affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
<region type="state">Manitoba</region>
</placeName>
</affiliation>
</author>
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<series><title level="j">Neurology</title>
<idno type="eISSN">1526-632X</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Age Factors</term>
<term>Cohort Studies</term>
<term>Comorbidity</term>
<term>Female</term>
<term>Hospitalization (statistics & numerical data)</term>
<term>Hospitalization (trends)</term>
<term>Humans</term>
<term>Length of Stay (statistics & numerical data)</term>
<term>Length of Stay (trends)</term>
<term>Male</term>
<term>Manitoba (epidemiology)</term>
<term>Middle Aged</term>
<term>Multiple Sclerosis (epidemiology)</term>
<term>Multiple Sclerosis (therapy)</term>
<term>Sex Factors</term>
<term>Socioeconomic Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Comorbidité</term>
<term>Durée du séjour ()</term>
<term>Durée du séjour (tendances)</term>
<term>Facteurs de l'âge</term>
<term>Facteurs sexuels</term>
<term>Facteurs socioéconomiques</term>
<term>Femelle</term>
<term>Hospitalisation ()</term>
<term>Hospitalisation (tendances)</term>
<term>Humains</term>
<term>Manitoba (épidémiologie)</term>
<term>Mâle</term>
<term>Sclérose en plaques ()</term>
<term>Sclérose en plaques (épidémiologie)</term>
<term>Études de cohortes</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Manitoba</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Multiple Sclerosis</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term>
<term>Length of Stay</term>
</keywords>
<keywords scheme="MESH" qualifier="tendances" xml:lang="fr"><term>Durée du séjour</term>
<term>Hospitalisation</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Multiple Sclerosis</term>
</keywords>
<keywords scheme="MESH" qualifier="trends" xml:lang="en"><term>Hospitalization</term>
<term>Length of Stay</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Manitoba</term>
<term>Sclérose en plaques</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Age Factors</term>
<term>Cohort Studies</term>
<term>Comorbidity</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sex Factors</term>
<term>Socioeconomic Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Comorbidité</term>
<term>Durée du séjour</term>
<term>Facteurs de l'âge</term>
<term>Facteurs sexuels</term>
<term>Facteurs socioéconomiques</term>
<term>Femelle</term>
<term>Hospitalisation</term>
<term>Humains</term>
<term>Mâle</term>
<term>Sclérose en plaques</term>
<term>Études de cohortes</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b>
</p>
<p>We aimed to describe hospitalizations in the multiple sclerosis (MS) population, and to evaluate temporal trends in hospitalizations in the MS population compared to the general population.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>Using population-based administrative data, we identified 5,797 persons with MS and a matched general population cohort of 28,769 persons. Using general linear models, we evaluated temporal trends in hospitalization rates and length of stay in the 2 populations over the period 1984-2011.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>In 1984 the hospitalization rate was 35 per 100 person-years in the MS population and 10.5 in the matched population (relative risk [RR] 3.33; 95% confidence interval: 1.67-6.64). Over the study period hospitalizations declined 75% in the MS population but only 41% in the matched population. The proportion of hospitalizations due to MS declined substantially from 43.4% in 1984 to 7.8% in 2011. The 3 most common non-MS-related reasons for admission in the MS population were diseases of the digestive, genitourinary, and circulatory systems. Admissions for bacterial pneumonia, influenza, urinary tract infections, and pressure ulcers occurred more often in the MS population than in the general population, while admissions for circulatory system disease and neoplasms occurred less often. Older age, male sex, and lower socioeconomic status were associated with increased hospitalization rates for non-MS-related reasons.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Although hospitalization rates have declined dramatically in the MS population over the last quarter century, they remain higher than in the general population. Admissions for MS-related reasons now constitute only a small proportion of the reasons for hospitalization.</p>
</div>
</front>
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<Title>Neurology</Title>
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<ELocationID EIdType="doi" ValidYN="Y">10.1212/WNL.0000000000000753</ELocationID>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">We aimed to describe hospitalizations in the multiple sclerosis (MS) population, and to evaluate temporal trends in hospitalizations in the MS population compared to the general population.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Using population-based administrative data, we identified 5,797 persons with MS and a matched general population cohort of 28,769 persons. Using general linear models, we evaluated temporal trends in hospitalization rates and length of stay in the 2 populations over the period 1984-2011.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In 1984 the hospitalization rate was 35 per 100 person-years in the MS population and 10.5 in the matched population (relative risk [RR] 3.33; 95% confidence interval: 1.67-6.64). Over the study period hospitalizations declined 75% in the MS population but only 41% in the matched population. The proportion of hospitalizations due to MS declined substantially from 43.4% in 1984 to 7.8% in 2011. The 3 most common non-MS-related reasons for admission in the MS population were diseases of the digestive, genitourinary, and circulatory systems. Admissions for bacterial pneumonia, influenza, urinary tract infections, and pressure ulcers occurred more often in the MS population than in the general population, while admissions for circulatory system disease and neoplasms occurred less often. Older age, male sex, and lower socioeconomic status were associated with increased hospitalization rates for non-MS-related reasons.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Although hospitalization rates have declined dramatically in the MS population over the last quarter century, they remain higher than in the general population. Admissions for MS-related reasons now constitute only a small proportion of the reasons for hospitalization.</AbstractText>
<CopyrightInformation>© 2014 American Academy of Neurology.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Marrie</LastName>
<ForeName>Ruth Ann</ForeName>
<Initials>RA</Initials>
<AffiliationInfo><Affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada. rmarrie@hsc.mb.ca.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Elliott</LastName>
<ForeName>Lawrence</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Marriott</LastName>
<ForeName>James</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cossoy</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Blanchard</LastName>
<ForeName>James</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tennakoon</LastName>
<ForeName>Aruni</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yu</LastName>
<ForeName>Nancy</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>From the Departments of Internal Medicine (R.A.M., J.M., M.C.) and Community Health Sciences (R.A.M., L.E., J.B., A.T., N.Y.), University of Manitoba, Winnipeg; and Epidemiology and Surveillance (N.Y.), Public Health and Primary Care Division, Manitoba Health, Winnipeg, Manitoba, Canada.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>08</Month>
<Day>01</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Neurology</MedlineTA>
<NlmUniqueID>0401060</NlmUniqueID>
<ISSNLinking>0028-3878</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015897" MajorTopicYN="N">Comorbidity</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
<QualifierName UI="Q000639" MajorTopicYN="N">trends</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007902" MajorTopicYN="N">Length of Stay</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
<QualifierName UI="Q000639" MajorTopicYN="N">trends</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008350" MajorTopicYN="N" Type="Geographic">Manitoba</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009103" MajorTopicYN="N">Multiple Sclerosis</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012737" MajorTopicYN="N">Sex Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012959" MajorTopicYN="N">Socioeconomic Factors</DescriptorName>
</MeshHeading>
</MeshHeadingList>
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<Month>8</Month>
<Day>3</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<Day>3</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2014</Year>
<Month>12</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
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<affiliations><list><country><li>Canada</li>
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<tree><country name="Canada"><region name="Manitoba"><name sortKey="Marrie, Ruth Ann" sort="Marrie, Ruth Ann" uniqKey="Marrie R" first="Ruth Ann" last="Marrie">Ruth Ann Marrie</name>
</region>
<name sortKey="Blanchard, James" sort="Blanchard, James" uniqKey="Blanchard J" first="James" last="Blanchard">James Blanchard</name>
<name sortKey="Cossoy, Michael" sort="Cossoy, Michael" uniqKey="Cossoy M" first="Michael" last="Cossoy">Michael Cossoy</name>
<name sortKey="Elliott, Lawrence" sort="Elliott, Lawrence" uniqKey="Elliott L" first="Lawrence" last="Elliott">Lawrence Elliott</name>
<name sortKey="Marriott, James" sort="Marriott, James" uniqKey="Marriott J" first="James" last="Marriott">James Marriott</name>
<name sortKey="Tennakoon, Aruni" sort="Tennakoon, Aruni" uniqKey="Tennakoon A" first="Aruni" last="Tennakoon">Aruni Tennakoon</name>
<name sortKey="Yu, Nancy" sort="Yu, Nancy" uniqKey="Yu N" first="Nancy" last="Yu">Nancy Yu</name>
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Dramatically changing rates and reasons for hospitalization in multiple sclerosis.

Dramatically changing rates and reasons for hospitalization in multiple sclerosis.

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